We investigated the relationship between magnesium levels in red blood cells and chronic fatigue syndrome (CFS). A case-control study revealed that CFS patients had lower magnesium levels than healthy individuals.
In a randomized, double-blind trial, 32 CFS patients received either magnesium sulphate or a placebo for six weeks. Those treated with magnesium reported significant improvements in energy, emotional wellbeing, and pain relief, with twelve out of fifteen feeling better.
In contrast, only three out of seventeen patients on placebo reported any improvement. Overall, these findings suggest that magnesium treatment may positively impact the wellbeing of those suffering from CFS.
Read More
7
Magnesium sulfate shows potential benefits
[A case of chronic fatigue syndrome who showed a beneficial effect by intravenous administration of magnesium sulphate].
We aimed to understand the effects of magnesium sulfate treatment on a patient with chronic fatigue syndrome. The case involved a 29-year-old woman experiencing severe fatigue alongside various symptoms, including swelling lymph nodes and muscle pain.
After other treatments failed to provide relief, we administered magnesium sulfate intravenously once a week. Remarkably, after six weeks, the patient reported a significant reduction in fatigue and improved daily functioning, eventually leading to her discharge from the hospital.
Read More
7
Magnesium shows limited benefit for fatigue
Magnesium status and parameters of the oxidant-antioxidant balance in patients with chronic fatigue: effects of supplementation with magnesium.
We investigated how magnesium levels relate to chronic fatigue by studying 93 patients with unexplained fatigue.
Around 47% of participants showed magnesium deficiency, linked to reduced plasma antioxidant capacity.
Although magnesium supplementation didn't increase blood glutathione levels, we observed improved magnesium stores and vitamin E levels.
However, this did not equate to a significant boost in antioxidant activity or a decrease in lipid vulnerability. Therefore, while magnesium may help improve some parameters, it is not a panacea for chronic fatigue syndrome.
Read More
Most Useful Reviews
9
Pleasant side effects
2 people found this helpful
This is a good chelate formula I started taking for a doctor-prescribed course. Its pleasant side effects include helping to cope with chronic fatigue! One minor drawback is that the capsules are a bit large, making them challenging to swallow at times.
Read More
9
Health improvement
Magnesium Glycinate Chelate has met all my expectations. My sleep has improved and fatigue has notably decreased. I take magnesium with meals and I’m very pleased with the improvement in my health.
Read More
7.5
Calming effect
69 people found this helpful
Quality product in great shape. Magnesium glycinate has an excellent calming and relaxing effect and helps to cope with chronic fatigue.
We investigated the relationship between magnesium levels in red blood cells and chronic fatigue syndrome (CFS). A case-control study revealed that CFS patients had lower magnesium levels than healthy individuals.
In a randomized, double-blind trial, 32 CFS patients received either magnesium sulphate or a placebo for six weeks. Those treated with magnesium reported significant improvements in energy, emotional wellbeing, and pain relief, with twelve out of fifteen feeling better.
In contrast, only three out of seventeen patients on placebo reported any improvement. Overall, these findings suggest that magnesium treatment may positively impact the wellbeing of those suffering from CFS.
Read More
7
Magnesium shows limited benefit for fatigue
Magnesium status and parameters of the oxidant-antioxidant balance in patients with chronic fatigue: effects of supplementation with magnesium.
We investigated how magnesium levels relate to chronic fatigue by studying 93 patients with unexplained fatigue.
Around 47% of participants showed magnesium deficiency, linked to reduced plasma antioxidant capacity.
Although magnesium supplementation didn't increase blood glutathione levels, we observed improved magnesium stores and vitamin E levels.
However, this did not equate to a significant boost in antioxidant activity or a decrease in lipid vulnerability. Therefore, while magnesium may help improve some parameters, it is not a panacea for chronic fatigue syndrome.
Read More
7
Magnesium sulfate shows potential benefits
[A case of chronic fatigue syndrome who showed a beneficial effect by intravenous administration of magnesium sulphate].
We aimed to understand the effects of magnesium sulfate treatment on a patient with chronic fatigue syndrome. The case involved a 29-year-old woman experiencing severe fatigue alongside various symptoms, including swelling lymph nodes and muscle pain.
After other treatments failed to provide relief, we administered magnesium sulfate intravenously once a week. Remarkably, after six weeks, the patient reported a significant reduction in fatigue and improved daily functioning, eventually leading to her discharge from the hospital.
We explored the effects of magnesium on chronic fatigue syndrome (CFS), a condition marked by extended periods of debilitating fatigue. While there’s no definitive therapy established for CFS, our review of clinical trials reveals that magnesium treatment has shown promise, enhancing the well-being of some patients.
Other treatments like acyclovir have proven ineffective, and although intravenous immunoglobulin therapy shows potential, its results remain debated. We recognize that restoring immune function may be a piece of the puzzle, but overall, the effectiveness of magnesium for treating CFS symptoms is yet to be firmly established.
Read More
4
Limited magnesium effectiveness in CFS
Complementary and alternative medicine for patients with chronic fatigue syndrome: a systematic review.
We systematically reviewed randomized controlled trials on complementary and alternative medicine (CAM) treatments for chronic fatigue syndrome (CFS).
Although 26 studies involving over 3,000 participants explored various therapies, the findings showed limited effectiveness overall.
While some treatments like massage and specific dietary supplements had some positive effects, most failed to provide significant benefits.
Notably, magnesium showed potential, but due to small sample sizes and biases in the studies, we can't make firm conclusions just yet. More rigorous studies are needed to confirm these effects.
Read More
User Reviews
USERS' SCORE
Good
Based on 7 Reviews
8
All Reviews
Positive Reviews
Negative Reviews
9
Pleasant side effects
2 people found this helpful
This is a good chelate formula I started taking for a doctor-prescribed course. Its pleasant side effects include helping to cope with chronic fatigue! One minor drawback is that the capsules are a bit large, making them challenging to swallow at times.
Read More
9
Health improvement
Magnesium Glycinate Chelate has met all my expectations. My sleep has improved and fatigue has notably decreased. I take magnesium with meals and I’m very pleased with the improvement in my health.
Read More
7.5
Calming effect
69 people found this helpful
Quality product in great shape. Magnesium glycinate has an excellent calming and relaxing effect and helps to cope with chronic fatigue.
Read More
7.5
Large capsules
20 people found this helpful
A good chelating formula purchased for a course prescribed by my doctor due to its pleasant side effects - helping to cope with chronic fatigue! One downside is that the capsules are rather large, making them difficult to swallow at times, even with water.
Read More
7.5
Improved sleep
Since taking magnesium, I’ve noticed an improvement in my pain and fatigue, and I sleep quite well. It’s easy to take and completely natural.
Chronic Fatigue Syndrome (CFS), also known as Myalgic Encephalomyelitis (ME), is a complex and debilitating condition characterized by profound fatigue that doesn’t improve with rest and worsens with physical or mental activity. This crippling fatigue is often accompanied by a variety of symptoms, including sleep disturbances, cognitive difficulties, muscle pain, and joint pain. Unlike typical tiredness, the fatigue experienced in CFS is long-lasting, and it can significantly hinder everyday activities and overall quality of life.
The precise cause of CFS remains unknown, but it is believed to be influenced by a combination of genetic, environmental, immunological, and psychological factors. Diagnosis primarily relies on a careful assessment of symptoms, as there are no definitive laboratory tests available. Treatment options focus on symptom management and may include lifestyle changes, physical therapy, medication for pain management, and cognitive behavioral therapy. Given the complexity and variability of the condition, individuals with CFS should consult healthcare professionals who specialize in this area to develop personalized management strategies.
Magnesium is a chemical element with the symbol Mg and atomic number 12. It is a lightweight, silvery-white metal that is a member of the alkaline earth metals group. Often classified as one of the most abundant elements in the Earth's crust, magnesium plays a crucial role in various biological functions and is essential for living organisms. In nature, magnesium can be found in large quantities, primarily in minerals such as dolomite and magnesite, and it is also present in seawater.
In terms of health benefits, magnesium is vital for numerous metabolic processes, including energy production, DNA synthesis, and muscle function. It contributes to bone health, helps regulate blood pressure, and supports bone formation by promoting the effects of vitamin D. The recommended dietary allowance (RDA) for magnesium varies by age and gender, but it is generally important to include magnesium-rich foods like leafy greens, nuts, seeds, and whole grains in your diet to ensure adequate intake. For those who may not receive enough magnesium through their diet alone, supplements are also available; however, it is advisable to consult a healthcare professional before starting any supplementation.
While there is ongoing research into the potential benefits of magnesium for various health conditions, including Chronic Fatigue Syndrome (CFS), definitive conclusions remain elusive. Magnesium plays a critical role in energy production, muscle function, and overall metabolism, which suggests it may provide some support for those suffering from CFS. Some anecdotal evidence and small-scale studies suggest that magnesium supplementation could help alleviate certain symptoms associated with fatigue, particularly if a deficiency is present. However, further extensive clinical studies are needed to establish a clear link between magnesium supplementation and improvement in CFS symptoms.
It's important for individuals considering magnesium supplementation to consult with a healthcare professional. They can determine individual needs and whether magnesium may be beneficial based on personal health profiles and existing conditions. Additionally, magnesium should not be viewed as a standalone solution for Chronic Fatigue Syndrome; a comprehensive approach that includes lifestyle changes, a balanced diet, and other treatments may be necessary for managing symptoms effectively.
Based on user reviews, the timeframe for seeing results from magnesium supplements for Chronic Fatigue Syndrome can vary. Several users have reported improvements shortly after starting their regimen, often within a few days to a few weeks. For instance, one reviewer mentioned a noticeable decrease in fatigue and improved sleep shortly after beginning their magnesium intake Read Review. Another user also noted improvements in pain and fatigue along with better sleep quality after taking magnesium Read Review.
However, it is essential to note that individual experiences can differ significantly. While many users found the magnesium glycinate to be effective in alleviating their symptoms, there was at least one user who reported feeling more fatigued after taking it, indicating that this supplement might not work for everyone Read Review. Therefore, as with most supplements, it’s advisable to monitor personal responses and adjust as necessary.
The evidence surrounding magnesium as a treatment for Chronic Fatigue Syndrome (CFS) is promising but not definitive. A systematic review of randomized controlled trials highlighted that while magnesium has shown potential in enhancing the well-being of some CFS patients, the findings are often limited due to small sample sizes and biases in the studies [1]. Some investigations suggest that magnesium deficiency is prevalent among those with unexplained fatigue, and supplementation could result in improved magnesium stores, though it does not significantly boost antioxidant activity or overall fatigue levels [2].
Moreover, a randomized double-blind trial indicated that patients receiving magnesium sulfate reported notable improvements in energy and emotional well-being compared to a placebo group [5]. However, the authors caution that while magnesium may alleviate some symptoms, it is not a cure-all for CFS [4]. Overall, while magnesium shows some promise, more extensive and rigorous studies are necessary to establish its effectiveness as a reliable treatment option for chronic fatigue syndrome.
Based on user reviews, many individuals have reported significant improvements in symptoms related to chronic fatigue after taking magnesium glycinate. Users frequently mention experiencing a notable decrease in fatigue levels and enhanced sleep quality. One reviewer noted, "My sleep has improved and fatigue has notably decreased," which highlights the direct correlation many have drawn between magnesium intake and better health outcomes Read Review. Others have echoed similar sentiments, emphasizing a calming effect that aids in coping with fatigue, making it a part of their routine during stressful periods Read ReviewRead Review.
However, it’s important to note that experiences can vary significantly among users. While the majority report positive outcomes, one user expressed disappointment, saying that they felt more fatigued after taking the supplement, illustrating that magnesium may not be universally effective Read Review. As a result, those considering magnesium supplements should monitor their personal reactions closely and consult with a healthcare provider when necessary.
Based on user reviews, many individuals report positive experiences when combining magnesium glycinate with other supplements or treatments for managing Chronic Fatigue Syndrome. For instance, users have noted that this supplement not only supports their overall well-being but also enhances the effectiveness of their prescribed courses, helping alleviate fatigue and improve sleep quality Read ReviewRead Review. One reviewer mentioned that magnesium glycinate has a calming effect that assists them during stressful periods, implying that it serves as a beneficial adjunct to other health regimens aimed at managing fatigue Read Review.
However, individual experiences can vary widely. While many users report significant improvements, such as decreased fatigue and better sleep when incorporating magnesium into their supplement routine, there have been instances of users experiencing the opposite effect. One reviewer indicated that they felt more fatigued after taking magnesium, highlighting that it may not work for everyone Read Review. Consequently, individuals looking to combine supplements should monitor their responses closely and consider consulting a healthcare professional for the best personalized approach.
Based on user reviews, many individuals have reported positive experiences with magnesium supplementation for alleviating symptoms associated with Chronic Fatigue Syndrome. Users commonly mention that magnesium glycinate, in particular, has been effective in improving their sleep and reducing feelings of fatigue. For instance, one user noted, "my sleep has improved and fatigue has notably decreased," after incorporating magnesium into their routine, suggesting a beneficial dosage when taken alongside meals Read Review.
Others highlighted the calming and relaxing effects of magnesium, indicating that it significantly helps in coping with chronic fatigue Read Review. However, experiences can vary—one user reported increased fatigue after just one pill, illustrating that the right dosage may differ between individuals and emphasizing the importance of consulting with a healthcare provider for personalized recommendations Read Review. Overall, while many users have found relief with magnesium supplementation, finding the optimal dose is essential for effectiveness.
9
Health improvement
Magnesium Glycinate Chelate has met all my expectations. My sleep has improved and fatigue has notably decreased. I take magnesium with meals and I’m very pleased with the improvement in my health.
7.5
Improved sleep
Since taking magnesium, I’ve noticed an improvement in my pain and fatigue, and I sleep quite well. It’s easy to take and completely natural.
2
Increased fatigue
Unfortunately, it did not work for me. After taking just one pill, I felt even more fatigued and drowsy for several days.
7.5
Calming effect
69 people found this helpful
Quality product in great shape. Magnesium glycinate has an excellent calming and relaxing effect and helps to cope with chronic fatigue.
6
Stress relief
This magnesium is gentle on my stomach and helps reduce fatigue, stress, and muscle spasms. I highly recommend it, especially during periods of high mental and physical stress.
9
Pleasant side effects
2 people found this helpful
This is a good chelate formula I started taking for a doctor-prescribed course. Its pleasant side effects include helping to cope with chronic fatigue! One minor drawback is that the capsules are a bit large, making them challenging to swallow at times.
4
Limited magnesium effectiveness in CFS
Complementary and alternative medicine for patients with chronic fatigue syndrome: a systematic review.
We systematically reviewed randomized controlled trials on complementary and alternative medicine (CAM) treatments for chronic fatigue syndrome (CFS).
Although 26 studies involving over 3,000 participants explored various therapies, the findings showed limited effectiveness overall.
While some treatments like massage and specific dietary supplements had some positive effects, most failed to provide significant benefits.
Notably, magnesium showed potential, but due to small sample sizes and biases in the studies, we can't make firm conclusions just yet. More rigorous studies are needed to confirm these effects.
7
Magnesium shows limited benefit for fatigue
Magnesium status and parameters of the oxidant-antioxidant balance in patients with chronic fatigue: effects of supplementation with magnesium.
We investigated how magnesium levels relate to chronic fatigue by studying 93 patients with unexplained fatigue.
Around 47% of participants showed magnesium deficiency, linked to reduced plasma antioxidant capacity.
Although magnesium supplementation didn't increase blood glutathione levels, we observed improved magnesium stores and vitamin E levels.
However, this did not equate to a significant boost in antioxidant activity or a decrease in lipid vulnerability. Therefore, while magnesium may help improve some parameters, it is not a panacea for chronic fatigue syndrome.
8
Magnesium potentially benefits CFS patients
Red blood cell magnesium and chronic fatigue syndrome.
We investigated the relationship between magnesium levels in red blood cells and chronic fatigue syndrome (CFS). A case-control study revealed that CFS patients had lower magnesium levels than healthy individuals.
In a randomized, double-blind trial, 32 CFS patients received either magnesium sulphate or a placebo for six weeks. Those treated with magnesium reported significant improvements in energy, emotional wellbeing, and pain relief, with twelve out of fifteen feeling better.
In contrast, only three out of seventeen patients on placebo reported any improvement. Overall, these findings suggest that magnesium treatment may positively impact the wellbeing of those suffering from CFS.
We explored the effects of magnesium on chronic fatigue syndrome (CFS), a condition marked by extended periods of debilitating fatigue. While there’s no definitive therapy established for CFS, our review of clinical trials reveals that magnesium treatment has shown promise, enhancing the well-being of some patients.
Other treatments like acyclovir have proven ineffective, and although intravenous immunoglobulin therapy shows potential, its results remain debated. We recognize that restoring immune function may be a piece of the puzzle, but overall, the effectiveness of magnesium for treating CFS symptoms is yet to be firmly established.
References
Alraek T, Lee MS, Choi TY, Cao H, Liu J. Complementary and alternative medicine for patients with chronic fatigue syndrome: a systematic review. BMC Complement Altern Med. 2011;11:87. doi:10.1186/1472-6882-11-87
Manuel y Keenoy B, Moorkens G, Vertommen J, Noe M, Nève J, et al. Magnesium status and parameters of the oxidant-antioxidant balance in patients with chronic fatigue: effects of supplementation with magnesium. J Am Coll Nutr. 2000;19:374.
Takahashi H, Imai K, Katanuma A, Sugaya T, Hisano K, et al. [A case of chronic fatigue syndrome who showed a beneficial effect by intravenous administration of magnesium sulphate]. Arerugi. 1992;41:1605.
Uchida A. [Therapy of chronic fatigue syndrome]. Nihon Rinsho. 1992;50:2679.
Cox IM, Campbell MJ, Dowson D. Red blood cell magnesium and chronic fatigue syndrome. Lancet. 1991;337:757.